The Foundation is funding six new ARSACS research projects

In Research in 2014 by ARSACS

The Foundation is pleased to announce that the following six new research projects will be funded for 2014-2015: “The use of KO and KI mice, a human fibroblast model and Sacs mini-gene in the search of a treatment for ARSACS” – Bernard Brais. “Role of neurofilaments and mitochondria in the pathogenic cascade of ARSACS: Relevant biomarkers for therapeutic development” – …

Preliminary work with Olivier Lambercy from Zurich paid off

In Research in 2014 by ARSACS

October 17,2014. Following a visit by Olivier Lambercy, a Swiss researcher to Saguenay back in September 2012 to present research from his laboratory, we are pleased that the preliminary work has paid off. We are beginning the process of analyzing the results of its tool for the entire cohort but already the pilot results are promising.Test à Saguenay. Interesting, right? …

ARSACS research team article published in the Oxford Journals

In Research in 2014 by ARSACS

October 06,2014-The ARSACS research team article, under the direction of Dr. Bernard Brais, has been published in the Oxford Journals of the prestigious Oxford University. The abstract of the article“Sacs knockout mice present pathophysiological defects underlying autosomal recessive spastic ataxia of Charlevoix-Saguenay”can be found in the Human Molecular Genetics.Full version. Interesting, right? Share with your friends & followers / Intéressant, …

Hiring of a project manager

In Research in 2014 by ARSACS

July 27, 2014. As a follow-up to a meeting held on July 14 2014 with some Board members, the Foundation will hire a project manager as soon as possible. The project manager will be responsible to accelerate the overall drug development activities for ARSACS. Interesting, right? Share with your friends & followers / Intéressant, non? Partagez avec vos amis:

Outcome of the Board meeting

In Research in 2014 by ARSACS

June 24, 2014. At the meeting of the Board held on 9 June in Montreal, there was discussion on the new cell model being developped and its potential use for screening large banks of therapeutic molecules. The new strategy being pursued and its first results were also discussed. These results are promising. Unfortunateluy, this new strategy and its results cannot …

Dr. Paola Giunti receives research funding

In Research in 2014 by ARSACS

The Foundation is pleased to announce that it will fund the research of Dr. Paola Giunti (ULC Institute of Neurology and National Hospital for Neurology and Neurosurgery, London, UK) under its current research funding program. Her work entitled “Design and Validation of a Custom Amplicon Panel for the Diagnosis of Spastic ARSACS and other ataxias” should contribute to diagnose ARSACS …

Meeting concerning the development of a possible drug

In Research in 2014 by ARSACS

As previously mentioned, a meeting for drug discovery work related to the sacsin will be held in Montreal. The meeting has been scheduled for July 14, 2014. The sacsin is the protein involved in ARSACS. Interesting, right? Share with your friends & followers / Intéressant, non? Partagez avec vos amis:

Millipore signs a commercialization agreement

In Research in 2014 by ARSACS

A commercialization agreement of the sacsin antibody was signed between Millipore and one of the ARSACS research team members. Millipore is a large US-based company and a major distibutor of commercial antibodies. With this agreement, the Foundation expects that other new ARSACS research will be undertaken that will eventually lead to interesting results. Interesting, right? Share with your friends & …

BBRC in the UK funding ARSACS related research

In Research in 2014 by ARSACS

Dr Paul Chapple, a member of the Foundation research team located in London, has received funding from the Biotechnology and Bioscience Research Council in the UK to better understand the sacsin’s role in mitochondrial dynamics, which is an important element in ARSACS research. The funding will support a postdoctoral researcher for three years. The project is titled ” Chaperoning Drp1 …

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Research results analysis

In Research in 2014 by ARSACS

Members of the ARSACS research team, Dre Roxanne Larivière, Rébecca Gaudet and Dr Bernard Brais,analyze the latest results of the research. Interesting, right? Share with your friends & followers / Intéressant, non? Partagez avec vos amis: