Exploring Neuronal Roles for Sacsin: from Dendritic Spines to Neuronal Polarity- Dr. Bernard Brais

In Current Research by ARSACS

The focus will be on

Aim 1. The objective is to submit a paper that will elucidate the role of Sacsin and EndoB2 in dendritic spines that will include our BioID results.

Aim 2. We will explore if a neuronal polarity defect in cytoskeletal protein trafficking might also be an important aspect of
ARSACS pathophysiology.

Duration: One year
Grant $80,000

Contact

Dr. Bernard Brais

Dr. Bernard Brais

Dr. Bernard Brais, co-director of the neuromuscular group of the Montreal Neurological Institute and Hospital
3801 University Street Montreal, Quebec, Canada H3A 2B4
Tel:(514)-398-3334; Email: bernard.brais@mcgill.ca

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