The Foundation is pleased to announce that the following six new research projects will be funded for 2014-2015:
- “The use of KO and KI mice, a human fibroblast model and Sacs mini-gene in the search of a treatment for ARSACS” – Bernard Brais.
- “Role of neurofilaments and mitochondria in the pathogenic cascade of ARSACS: Relevant biomarkers for therapeutic development” – Heather Durham.
- “Modelling ARSACS using induced pluripotent stem cell derived neurons with isogenic controls”- Paul Chapple.
- “Cellebellar output deficiencies in a mouse model of ARSACS” – Alanna Watt.
- “New emerging team on Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS): from models to treatment strategies” – Cynthia Gagnon.
- “A randomised delayed entry trial of intensive home-based speech therapy in ARSACS” – Matthis Synofzik.
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